# References; Linked-In Posts; White Papers

## Measurement Uncertainty

### How to measure Uncertainty of Measurement

Hello,

When you start working with all the
numbers, you see uncertainties, or confidence limits,
everywhere. Our goal is to determine if the patient
or QC mean and SD changed significantly. which makes
uncertainty of measurement critical ... as are significant
figures, by the way.

If we measure the percent low and high
risk patients each day, week and month for HbA1c, there are
uncertainties in each data set. For instance, in EP
Evaluator software, they calculate confidence limits for the mean
and SD saying: "95%
Confidence Interval for SD: In a sense, this measures the
"precision of the precision". It shows how much the
SD might vary if the precision
experiment was repeated with different experimental results.
The width of the confidence interval depends on two factors: N and the intrinsic SD
of the system. The reliability of the precision estimate
improves as N increases."

If you have other comments or questions
about MU, please send them. Or please join us on Thursday
at 2 PM for the online meeting.

Zoe

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