# References; Linked-In Posts; White Papers

## In search of ONE TRUTH

### 1. There is Only ONE Truth

There are many statistical processes to estimate bias or calculate sigma, but there is only ONE truth in the patient population. What do you think? What do you do? What is the best way to measure the truth?

It makes sense that if PATIENT samples produce the same results on four different instruments, then those instruments have the same bias, the same sigma value, and require the same quality control process to detect failure of acceptable risk criteria.

It does NOT make sense that each laboratory professional is free to choose different QC samples with no obligation to prove that they reflect patients, and then calculate bias as variation between the current measured mean and

[A] the peer group mean,

[B] the package insert mean, or

[C] the lab’s own historical mean or

[D] none of the above: don’t calculate bias at all -
estimate it from any proficiency program using any samples at any
time.

Aug. 14, 2018. Zoe Brooks

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